The design of fixtures for slot or slab machining operations and their clamping schemes is an intricate and highly static problem that entails workpiece deformation due to the clamping and machining forces. The numerous parameters, such as clamping and machining forces, von Misses stress, and workpiece deformation in the component, are of particular relevance in this context. A practical fixture layout must include the optimum values of clamping, machining forces, von misses stress and w/p deformation. More research is required to address the complex issue in the fixture design field. This paper explores to resolve a model of the workpiece-fixation system for the slot milling operation under cutting and clamping pressures through Finite Element Analysis. The workpiece-fixture system must use a finite element model to identify a relationship between the clamping forces and von Misses stress. To determine factors like workpiece deformation, von Misses stress, clamping forces, and machining forces, the usage of machining force is recommended. This work aims to minimize the magnitude of clamping, machining forces and deformation of the work piece for the slot milling process. The behavior of the workpiece's deformation and von Misses stress were discovered in this analysis. Computer-aided process planning and automation of fixture design are the driving forces behind this current study.